Shimadzu UK Limited Nexera Mikros

Micro‐Flow LC‐MS System


  • Increased sensitivity
  • Reduced sample volume
  • Unsurpassed robustness
  • User friendly
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Development of micro‐flow ESI for high sensitivity with high robustness

Technical Report

Nexera Mikros ‐ new micro‐flow LCMS system

Shimadzu @ Analytica

Visit us at Analytica Hall A1, booth 502

Nexera Mikros

Increased Sensitivity of a Micro‐Flow System with the Ruggedness of Standard HPLC


  • Increased sensitivity provides lower LOQs for more accurate quantitation in DMPK studies and lower LODs for detection of novel biomarkers
  • Micro sampling is less invasive to the patient while saving cost for delivery and storage
  • Ruggedness and ease of use of Nexera-Mikros increase throughput and lab efficiency
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Nexera™ Mikros and nSMOL™ Antibody BA Kit


  • The nSMOL Antibody BA Kit is a ready-to-use reagent kit for collecting monoclonal antibodies from blood or other biological samples
  • Fab-derived peptides are quantified via MRM measurement on a high-sensitivity mass spectrometer.
  • Nexera Mikros achieved signal intensities 12 times higher than with conventional flow rates, with a corresponding lower limit of detection of 0.025 μg/mL and good linearity.
  • The Nexera Mikros system is ideal for low-level quantitation of peptides by LCMS.
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* Actually it's the smallest (footprint) and lightest FTIR spectrophotometer in the world that can be used with optional products from other manufacturers.

Shimadzu UK Limited

Mill Court, Featherstone Road, Wolverton Mill South, Milton Keynes, Buckinghamshire MK12 5RD

• Sales Hotline: 01908 552 209 • Service Hotline: 01908 552 202
• Accounts: 01908 552 201 • Facsimile: 01908 552 211

UK Registration No. 5342169